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Schwannoma including epithelial elements mimicking pleomorphic adenoma of the submandibular gland on fine‐needle cytology: The first case report
Author(s) -
Tarjan Gabor
Publication year - 2015
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23229
Subject(s) - schwannoma , pleomorphic adenoma , myoepithelial cell , medicine , pathology , salivary gland , immunohistochemistry
Although most salivary gland tumors can be diagnosed accurately on fine‐needle aspiration, cytological evaluation of spindle cell lesions, including schwannomas, still poses a challenge. In salivary gland aspirates, the most important mimickers of schwannomas are the common pleomorphic adenomas/mixed tumors since these may yield abundant spindle‐shaped myoepithelial cells and only scant epithelial cells. Therefore, in spindle cell‐rich aspirates from the head and neck, diligent search for epithelial cells is recommended. Their presence traditionally favors pleomorphic adenoma and argues against a schwannoma. Herein, however, we report, for the first time, a schwannoma with epithelial elements (glandular schwannoma) in the submandibular gland, demonstrating that the presence of epithelial cells in a spindle cell‐rich aspirate may not always exclude a schwannoma. Diagn. Cytopathol. 2015;43:395–398. © 2014 Wiley Periodicals, Inc.