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Fine‐needle aspiration of metanephric adenoma of the kidney with clinical, radiographic and histopathologic correlation: A review
Author(s) -
Blanco Luis Z.,
Schein Caitlin O.,
Patel Tushar,
Heagley Dawn E.,
Cimbaluk David J.,
Reddy Vijaya,
Gattuso Paolo
Publication year - 2013
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.22962
Subject(s) - medicine , pathology , nuclear atypia , papillary renal cell carcinomas , fine needle aspiration , atypia , malignancy , adenoma , cytopathology , cytology , biopsy , kidney , carcinoma , immunohistochemistry
Metanephric adenoma of the kidney is an uncommon benign epithelial neoplasm with only a small number of reports that describe its cytologic features. We describe two additional cases of metanephric adenoma diagnosed on fine‐needle aspiration biopsy and review the available literature. Our cases showed similar cytology and were composed of cellular smears with numerous clusters of small, oval to round cells arranged in a microfollicular pattern and papillary configurations. The tumor cells had scant cytoplasm, fine chromatin and absent nucleoli. Psamomma bodies, nuclear atypia, cellular cpleomorphism, necrosis, and mitoses were absent. Because of the rarity of this tumor and the common cytologic features it shares with other lesions, including malignant tumors such as Wilms’ tumor and papillary renal cell carcinoma, awareness of the cytologic features of metanephric adenoma may aid in avoiding a diagnosis of malignancy, especially preoperatively, and in guiding the proper management for the patients. Diagn. Cytopathol. 2013;41:742–751. © 2013 Wiley Periodicals, Inc.