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Concurrent pleural infiltration by chronic lymphocytic leukemia and adenocarcinoma of unknown primary site diagnosed by effusion cytology
Author(s) -
Vrettos Ioannis,
Kamposioras Konstantinos,
Peridis Stamatios,
Aninos Dionisios,
Kazika Stella,
Spathis Aris,
Karakitsos Petros,
Papadopoulos Angelos
Publication year - 2014
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.22889
Subject(s) - medicine , pleural effusion , chronic lymphocytic leukemia , effusion , cytology , adenocarcinoma , complication , pathology , infiltration (hvac) , leukemia , cancer , surgery , physics , thermodynamics
Synchronous malignancies in a pleural effusion are rare. A case of concurrent pleural infiltration by adenocarcinoma of unknown primary site and chronic lymphocytic leukemia (CLL) is presented in this case study, which was diagnosed by effusion cytology. Pleural effusion is not an uncommon complication in patients with B‐CLL. Even in a pleural effusion rich in monoclonal lymphocytes, the presence of a second cancer must be excluded because this can be the main cause of mortality. The role of cytology in such cases is of paramount importance. Diagn. Cytopathol. 2014;42:151–155. © 2012 Wiley Periodicals, Inc.