Premium
Barr body in fine needle aspiration cytology of ovarian malignancies
Author(s) -
Agrawal Pallavi,
Dey Pranab
Publication year - 2012
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.21688
Subject(s) - medicine , cytology , fine needle aspiration cytology , fine needle aspiration , gynecology , pathology , biopsy
The Barr body is the inactive X chromosome in a female somatic cell. It is readily identified as plano‐convex structure of 2–3 micron in diameter on the periphery of the nuclear membrane. The aim of this study is to evaluate the significance of Barr body count in malignant ovarian tumors on fine needle aspiration cytology (FNAC) smears. In this retrospective study, Barr body was counted in FNAC smears of 20 successive malignant ovarian lesions and expressed as percentage. Mean (±SD) Barr body score was 2.4 ± 2.58. Minimum Barr body count was 1 and maximum was 9. The gross reduction of Barr body in ovarian neoplasms is an interesting cytomorphologic finding. Diagn. Cytopathol. 2012. © 2011 Wiley Periodicals, Inc.