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Adult granulosa cell tumor presenting as metastases to the pleural and peritoneal cavity
Author(s) -
Gupta Nalini,
Rajwanshi Arvind,
Dey Pranab,
Suri Vanita
Publication year - 2012
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.21675
Subject(s) - medicine , serous fluid , pathology , stromal cell , peritoneal fluid , pleural effusion , ascites , ascitic fluid , cytology , pleural cavity , pleural fluid , stromal tumor , anatomy
Ovarian tumors of sex‐cord stromal derivation rarely exfoliate malignant cells in serous effusions. Adult granulosa cell tumor (AGCT) often presents as a stage I disease and association with ascites is about 10%. AGCT is rarely known to exfoliate tumor cells in the ascitic fluid. Exfoliation of malignant cells in the pleural fluid is rarer and has not been described previously in literature to the best of our knowledge. We report a case of AGCT presenting as stage IV disease with exfoliation of malignant cells in the pleural and ascitic fluid with exudative effusions. We wish to emphasize on cytomorphologic features of AGCT to differentiate the same from malignant epithelial tumors. A precise diagnosis in such a case may be possible on serous body fluid cytology with a combined clinical and cytopathologic approach. Diagn. Cytopathol. 2012. © 2011 Wiley Periodicals, Inc.