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Glandular neoplasia and borderline endocervical reporting rates before and after conversion to the SurePath TM liquid‐based cytology (LBC) system
Author(s) -
Burnley C.,
Dudding N.,
Parker M.,
Parsons P.,
Whitaker C. J.,
Young W.
Publication year - 2011
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.21471
Subject(s) - medicine , liquid based cytology , cytology , gynecology , cervical intraepithelial neoplasia , pathology , cervical cancer , cancer
Reporting rates for glandular neoplasia in 464,754 cervical samples reported at six laboratories in 12‐month periods before and after the implementation of Surepath™ LBC processing are compared. The introduction of LBC processing is seen to have resulted in a significant ( P = 0.001) increase in the detection rate for endocervical glandular neoplasia (from 2.2 per 10,000 tests to 3.9 per 10,000) while maintaining high levels of reporting specificity. An observed fall in the number of samples reported as showing borderline glandular neoplasia falls short of statistical significance, and the reporting of possible endometrial and ‘other’ glandular abnormalities appears to be unaffected. The underlying reasons for the observed improvement in detection of endocervical glandular neoplasia are discussed. Diagn. Cytopathol. 2011. © 2010 Wiley Periodicals, Inc.