Premium
Mediastinal epithelioid hemangioendothelioma metastatic to lymph nodes and pleural fluid: Report of a case
Author(s) -
Antic Tatjana,
Staerkel Gregg
Publication year - 2010
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.21162
Subject(s) - medicine , epithelioid hemangioendothelioma , pathology , pleural effusion , thyroid , lymph , hemangioendothelioma , metastatic carcinoma , epithelioid sarcoma , metastasis , soft tissue , immunohistochemistry , carcinoma , radiology , cancer
Epithelioid hemangioendothelioma is a rare mesenchymal tumor of vascular origin, classified as a sarcoma of intermediate malignant potential. Involvement of numerous sites of the body, including visceral organs, soft tissue, testis, skeleton, brain, meninges, and skin have been described. We report an unusual case of a mediastinal epithelioid hemangioendothelioma in a 65‐year‐old female initially presenting as a metastasis to lymph nodes of the hilar region and subsequently as a malignant pleural effusion. The patient had a complex history of papillary renal cell carcinoma, papillary thyroid carcinoma, and Waldenstrom's hyperglobulinemia making the diagnosis of metastatic epithelioid hemangioendothelioma difficult. Clinical, cytological and immunohistochemical features of this tumor are described with an emphasis on diagnostic pitfalls. Diagn. Cytopathol. 2010. © 2009 Wiley‐Liss, Inc.