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A correlation study on diagnostic endoscopic ultrasound‐guided fine‐needle aspiration of lymph nodes with histological and clinical diagnoses, the UCLA Medical Center experience
Author(s) -
Naini Bita V.,
Apple Sophia K.,
Presley Michelle,
Moatamed Neda A.
Publication year - 2008
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20825
Subject(s) - medicine , concordance , fine needle aspiration , lymph , radiology , endoscopic ultrasound , medical diagnosis , percutaneous , sampling (signal processing) , biopsy , pathology , computer vision , filter (signal processing) , computer science
Endoscopic ultrasound guided (EUS) FNA procedure has two aspects, the endoscopic sampling and the FNA interpretation. The two aspects of the procedure are performed in two different disciplines; gastroenterology (EUS) and pathology (FNA). The aim of this study was to evaluate the concordance, sensitivity, specificity, positive predictive (PPV), and negative predictive values (NPV). Sixty‐one EUS‐FNA procedures of the lymph nodes were analyzed by correlating the FNA results with histological or clinical diagnoses. The lymph nodes were divided in five groups; mediastinal, gastrohepatic, peripancreatic, portal, and perirectal. The study showed a concordance of 92% in mediastinal, 80% in gastrohepatic, 81% in peripancreatic, 95% in portal, and 100% in perirectal lymph nodes with an overall sensitivity of 84%, specificity of 92%, PPV of 88%, and NPV of 89%. In conclusion, EUS‐FNA offers an invaluable approach for diagnostic examination of the internal lymph nodes where percutaneous FNA is either difficult or impossible. impossible. Diagn. Cytopathol. 2008;36:460–466. © 2008 Wiley‐Liss, Inc.