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Hairy cell leukemia presenting as a discrete liver mass: Diagnosis by fine needle aspiration biopsy
Author(s) -
AlZa'abi Ali Mohammed,
Boerner Scott L.,
Geddie William
Publication year - 2008
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20760
Subject(s) - medicine , hairy cell leukemia , pancytopenia , fine needle aspiration , biopsy , hairy cell , bone marrow , pathology , leukemia , liver biopsy , spleen , radiology
Hairy cell leukemia, a chronic low‐grade lymphoproliferative disorder first recognized in mid 1920's typically involves the lymphoreticular system, especially the spleen and the bone marrow. Clinically, it tends to present with pancytopenia and splenomegaly. Liver involvement, if present, is usually in a sinusoidal and a periportal pattern. We report a case of hairy cell leukemia associated with a liver mass 20 years after the initial presentation. To our knowledge, this is the first case of hairy cell leukemia presenting as a solid liver mass diagnosed by a percutaneous ultrasound guided fine needle aspiration biopsy to be reported in the English literature. Diagn. Cytopathol. 2008;36:128–132. © 2008 Wiley‐Liss, Inc.