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Karyomegalic interstitial nephritis: A pitfall in urine cytology
Author(s) -
Palmer David,
Lallu Sharda,
Matheson Philip,
Bethwaite Peter,
Tompson Keneth
Publication year - 2007
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20603
Subject(s) - medicine , urine cytology , cytopathology , interstitial nephritis , nephritis , pathology , urine , chronic renal failure , cytology , kidney , cystoscopy , alternative medicine
A case of a 44‐yr‐old Maori female presenting with chronic renal failure due to karyomegalic interstitial nephritis is reported. To our knowledge, this is the first instance this disorder has been reported in a New Zealand Maori. Karyomegalic interstitial nephritis is a rare cause of progressive renal failure, which may be familial, and is frequently associated with a history of recurrent respiratory infections. The urine in this case contained large, pleomorphic cells, mimicking carcinoma. The case therefore illustrates a rare cause of chronic renal failure, and presents an important diagnostic pitfall in the practice of urine cytopathology. Diagn. Cytopathol. 2007;35:179–182. © 2007 Wiley‐Liss, Inc.