Cardiac angiosarcoma: Report of a case diagnosed by echocardiographic‐guided fine‐needle aspiration

The authors present a case of cardiac angiosarcoma diagnosed by fine‐needle aspiration (FNA) in a 33‐year‐old male. A percutaneous right atrial mass biopsy was performed via a right internal jugular venous approach and under echocardiographic guidance. FNA showed pleomorphic spindle‐shaped cells present singly and in small clusters in a background of hemorrhage. Occasional pseudo‐acini or microacinar structures were observed, that are lined with abnormal spindly to polygonal cells, indicative of vasoformative structures. Immunostain for CD31 was strongly positive. A diagnosis of cardiac angiosarcoma was made, following which, the patient underwent treatment with chemotherapy. Diagn. Cytopathol. 2007;35:164–166. © 2007 Wiley‐Liss, Inc.