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Barrett's esophagus with high‐grade dysplasia simulating metastatic adenocarcinoma in a fine needle aspiration biopsy
Author(s) -
Gutmann Edward J.,
Suriawinata Arief,
Gordon Stuart
Publication year - 2006
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20501
Subject(s) - medicine , esophagus , biopsy , adenocarcinoma , dysplasia , barrett's esophagus , esophageal adenocarcinoma , fine needle aspiration , metastatic adenocarcinoma , radiology , pathology , cancer
An endoscopic ultrasound examination, performed to rule out invasive esophageal carcinoma in a patient with a history of Barrett's esophagus with high‐grade dysplasia, disclosed an enlarged paraesophageal lymph node which was aspirated. The aspirate contained markedly atypical clustered large cells that displayed prominent nucleoli and mitoses, as well as lymphoid cells, suggestive of adenocarcinoma metastatic to a lymph node. The neoplastic‐appearing cells were, in fact, dysplastic glandular cells that the needle traversed en route to a reactive lymph node. The case represents a rare instance in which Barrett's esophagus with high‐grade dysplasia was discerned on fine needle aspiration (FNA) biopsy and highlights a potential pitfall in FNA. Diagn. Cytopathol. 2006;34:507–510. © 2006 Wiley‐Liss, Inc.