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Fine‐needle aspiration biopsy of a case of breast carcinoma with choriocarcinomatous features
Author(s) -
Siddiqui Noman H.,
Cabay Robert J.,
Salem Fadi
Publication year - 2006
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20485
Subject(s) - medicine , immunohistochemistry , fine needle aspiration , biopsy , breast carcinoma , carcinoma , estrogen receptor , human chorionic gonadotropin , gynecology , pathology , disease , oncology , breast cancer , cancer , hormone
Breast disease is of great concern to patients and health care providers alike. Malignancies of the breast and their various presentations can pose tremendous challenges with respect to early diagnosis and effective treatment. Carcinoma of the breast may appear in several forms and produce one or more ectopic substances. Breast carcinomas that display choriocarcinomatous differentiation and produce human chorionic gonadotropin are very rare. Less than a dozen such cases have been described in the medical literature to date. We report a case of breast carcinoma with choriocarcinomatous features, which is the first to show immunohistochemical evidence of the expression of both estrogen receptor and progesterone receptor. We also discuss the cytopathologic aspects observed and conduct a literature review. Diagn. Cytopathol. 2006;34:694–697. © 2006 Wiley‐Liss, Inc.