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Cytological diagnosis of primary leiomyosarcoma of bone: Case report
Author(s) -
Cohen Isaac,
Loberant Norman,
Goldfeld Moshe,
Volpin Gershon
Publication year - 2001
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2046
Subject(s) - medicine , leiomyosarcoma , soft tissue , differential diagnosis , intramedullary rod , pathology , radiography , primary bone , fine needle aspiration , lesion , radiology , anatomy , biopsy
We report on a case of primary leiomyosarcoma of the bone in a 77‐yr‐old man. The patient presented with a painful, enlarging mass in the left shoulder of 6 mo duration. Radiography and computed tomography (CT) revealed a large destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT‐guided fine‐needle aspiration biopsies (FNAB) of both the bony and soft‐tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle cells mixed with pleomorphic cells. The smooth muscle origin of the neoplastic cells was confirmed by immunocytochemical analysis. We describe the cytological features of this rare primary tumor of bone, and consider the differential diagnosis of spindle‐cell neoplasms. Diagn. Cytopathol. 25:239–243, 2001. © 2001 Wiley‐Liss, Inc.