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Fine‐needle aspiration cytology of salivary glands: Diagnostic pitfalls—revisited
Author(s) -
Rajwanshi Arvind,
Gupta Kirti,
Gupta Nalini,
Shukla Rajeev,
Srinivasan Radhika,
Nijhawan Raje,
Vasishta Rakesh
Publication year - 2006
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20353
Subject(s) - medicine , cytology , salivary gland , cytopathology , pathology , fine needle aspiration , fine needle aspiration cytology , salivary gland diseases , biopsy
Fine needle aspiration cytology (FNAC) of salivary gland lesions is a safe, effective diagnostic technique. Several amply illustrated reviews are available in the English literature. The reported diagnostic accuracy varies between 86% to 98%. The sensitivity ranges from 62% to 97.6% and specificity is higher from 94.3% to 100%. In this present study, we have analyzed 172 cases of salivary gland aspirates and the histopathological diagnosis was available in 45 cases. There was discordance in cytological and histopathological diagnosis in nine cases. Five cases had discrepancies in benign versus malignant diagnosis with four cases being false negative. The errors in these FNA diagnoses were due to sampling error, observational error and interpretational error. Therefore, this study illustrates high diagnostic accuracy of FNAC in salivary gland lesions and shows that FNAC offers valuable information that allows the planning of subsequent patient management. Diagn. Cytopathol. 2006;34:580–584. © 2006 Wiley‐Liss, Inc.