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Background features of endometrial carcinoma on ThinPrep® cytology
Author(s) -
Selvaggi Suzanne M.
Publication year - 2005
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20347
Subject(s) - medicine , carcinoma , diathesis , adenocarcinoma , biopsy , cytology , gynecology , pathology , gastroenterology , cancer , immunology
Conventional smear screening has had little impact on the detection of endometrial carcinoma. Recent studies on liquid‐based preparations show promise with increased detection rates of endometrial lesions. The purpose of this 2‐yr retrospective study (February 1, 2002–February 29, 2004) was to evaluate the background features on ThinPrep® slide preparations from endometrial carcinomas. During this period, 20 (0.06%) cases were diagnosed as adenocarcinoma, of which 15 (75%) showed endometrial carcinoma on cervical or vaginal biopsy. Classic tumor diathesis was present on the slides in 8 (53%) of the cases, the majority of which were from high‐grade tumors. In 1 (7%) case, the tumor diathesis consisted of precipitated protein in a watery background. Tumor diathesis was absent in 6 (40%) of the cases, the majority of which were low‐grade lesions. Background features on ThinPrep® Pap tests™ from patients with endometrial features range from classic tumor diathesis to clean; findings dependent on the histologic type and grade of the tumor and the extent of the disease process. Diagn. Cytopathol. 2005;33:162–165 © 2005 Wiley‐Liss, Inc.