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Intracytoplasmic and intranuclear Reinke's crystals in a testicular Leydig‐cell tumor diagnosed by fine‐needle aspiration cytology: A case report with review of the literature
Author(s) -
Jain M.,
Aiyer H.M.,
Bajaj P.,
Dhar S.
Publication year - 2001
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2029
Subject(s) - medicine , cytology , histopathology , leydig cell tumor , biopsy , pathology , fine needle aspiration , leydig cell , fine needle aspiration cytology , intracytoplasmic sperm injection , gynecology , biology , luteinizing hormone , pregnancy , hormone , in vitro fertilisation , genetics
We report on the cytopathologic findings of a Leydig‐cell tumor of the testis in a young adult male with no evidence of endocrine dysfunction. The preoperative diagnosis was based on fine‐needle aspiration cytology (FNAC) alone, which was subsequently confirmed on histopathology. The present case was of interest on account of the paucity of literature regarding the cytodiagnosis of this lesion. In addition, the finding of intracytoplasmic lipofuscin pigment and several intracytoplasmic as well as intranuclear Reinke's crystals served to clinch the diagnosis on FNA. Therefore, the use of FNAC, especially in the presence of diagnostic Reinke's crystals, may vitiate the need for more invasive biopsy procedures in the preoperative diagnosis of testicular Leydig‐cell tumors. Diagn. Cytopathol. 2001;25:162–164. © 2001 Wiley‐Liss, Inc.