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Metastatic extraocular sebaceous carcinoma with an occult primary
Author(s) -
Malhotra Purnima,
Arora Vinod K.,
Singh Navjeevan,
Bhatia Arati
Publication year - 2004
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20117
Subject(s) - sebaceous carcinoma , mucoepidermoid carcinoma , medicine , occult , pathology , carcinoma , lymph node , metastasis , primary tumor , cancer , alternative medicine
The cytological diagnosis of sebaceous carcinoma is based on the aspiration of tumor lobules with extensive sebaceous differentiation. However, these tumors may show a spectrum of cells ranging from basaloid to well‐differentiated sebaceous. Extraocular sebaceous carcinoma is an uncommon tumor. An occult primary at initial presentation has not been described previously. A 60‐yr old woman was referred to the fine‐needle aspiration (FNA) clinic with a submandibular mass. The cytological diagnosis was mucoepidermoid carcinoma. Histopathologically, it was a sebaceous carcinoma metastatic to the submandibular lymph node. No primary tumor was identified. Six months later, she presented with a nodule at the angle of her mouth and a recurrence of the submandibular swelling. FNA cytology (FNAC) and histopathologic examination revealed a primary cutaneous sebaceous carcinoma with submandibular lymph node metastasis. A metastatic sebaceous carcinoma in the submandibular region with limited sebaceous differentiation and occult primary is another pitfall in the cytomorphological diagnosis of mucoepidermoid carcinoma. Diagn. Cytopathol. 2004;31:326–329. © 2004 Wiley‐Liss, Inc.