Premium
Fine‐needle aspiration cytology in tuberculous lymphadenitis of patients with and without HIV infection
Author(s) -
Nayak Sujata,
Puranik Shaila C.,
Deshmukh Sanjay D.,
Mani Reeta,
Bhore Arvind V.,
Bollinger Robert C.
Publication year - 2004
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.20072
Subject(s) - medicine , tuberculous lymphadenitis , cytology , biopsy , tuberculosis , fine needle aspiration , pathology , fine needle aspiration cytology
A study of the cytologic features and role of fine‐needle aspiration cytology (FNAC) in tuberculous lymphadenitis (TBL) of 21 patients with HIV (group 1) and 21 patients without HIV (group 2) infection was undertaken. Four cytologic patterns were observed, of which necrotizing lymphadenitis (42.9%) and necrotizing suppurative lymphadenitis (28.6%) were predominant in group 1 while necrotizing granulomatous lymphadenitis (47.7%) and granulomatous lymphadenitis (23.8%) were more common in group 2. No pattern was found specific for either group. Zeihl‐Neelsen‐stained cytology smears of group 1 showed a much higher percentage of positively (61.9%) and a higher density of acid‐fast bacilli than group 2. Definitive diagnoses of TBL on FNAC could be provided in 61.9% of group 1 as against 9.5% of group 2. The need for culture or biopsy for definitive diagnosis was higher in group 2. In suspected TBL, diagnostic efficacy can be improved and the need for surgical biopsy reduced if material collected on FNA is also used for culture. Diagn. Cytopathol. 2004;31:204–206. © 2004 Wiley‐Liss, Inc.