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Cytology of small‐cell carcinoma of the uterine cervix in serous effusion: A report on two cases
Author(s) -
Khunamornpong Surapan,
Siriaunkgul Sumalee,
Suprasert Prapaporn
Publication year - 2001
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.1055
Subject(s) - medicine , effusion , pathology , pleural effusion , ascites , cervix , carcinoma , serous fluid , cytology , small cell carcinoma , lymphoma , differential diagnosis , large cell , adenocarcinoma , cancer , radiology , surgery
Cytologic features of 2 cases of small‐cell carcinoma of the uterine cervix in the body fluid are described. Case 1 was a 34‐yr‐old woman with a stage IIA cervical tumor. Pleural effusion developed 6 mo after initial diagnosis. Case 2 was a 38‐yr‐old woman with a stage IB tumor. Ascites was detected 11 mo after hysterectomy. Histologically, both cervical tumors were indistinguishable from small‐cell carcinoma of oat‐cell type in the lungs or other sites. Cytologically, the tumor cells in the pleural effusion of case 1 had characteristic features of small‐cell carcinoma, including nuclear molding. However, almost all tumor cells in the ascites of case 2 showed a single‐cell pattern mimicking malignant lymphoma. Mitotic figures and karyorrhetic bodies were occasionally seen. Nuclear molding was rarely identified. Small‐cell carcinoma should be included in the differential diagnosis of malignant effusions containing lymphoma‐like cells. Diagn. Cytopathol. 24:253–255, 2001. © 2001 Wiley‐Liss, Inc.