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Metastatic ovarian Sertoli‐cell tumor: FNA findings with immunohistochemistry
Author(s) -
Watson Brian,
Siegel Cary L.,
Ylagan Lourdes R.
Publication year - 2003
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.10369
Subject(s) - medicine , pathology , sertoli cell , immunohistochemistry , differential diagnosis , stromal cell , biopsy , ovary , spermatogenesis
A malignant Sertoli cell tumor of the ovary is a rare sex‐cord stromal derived neoplasm. Sertoli cell tumors account for ∼4% of Sertoli‐stromal cell tumors (Hsu et al., J Histochem Cytochem 1981;29:577–580). The diagnosis of this entity by fine‐needle aspiration and needle core biopsy can be difficult when the differential also includes a metastatic renal cell carcinoma, due to the overlap of both cytological and histological features. Here, we show that immunohistochemical staining on cytological material including alpha‐inhibin can be used to differentiate between these two malignant tumors. Diagn. Cytopathol. 2003;29:283–286. © 2003 Wiley‐Liss, Inc.