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Inflammatory fibroid polyp of the ileum causing intussusception: Report of two cases with emphasis on cytologic diagnosis
Author(s) -
Savargaonkar Pratima,
Morgenstern Nora,
Bhuiya Tawfiqal
Publication year - 2003
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.10258
Subject(s) - medicine , inflammatory fibroid polyp , differential diagnosis , pathology , intussusception (medical disorder) , abdominal pain , bowel obstruction , inflammatory pseudotumor , lesion , radiology , cytology , malignancy , leiomyoma , gastroenterology
Inflammatory fibroid polyp (IFP) of the gastrointestinal tract is a type of inflammatory pseudotumor or inflammatory myofibroblastic tumor that occurs most commonly in the stomach but also in the small and large bowel. Small‐bowel IFP usually presents with intussusception. The purpose of the current study is to describe cytological features of this lesion with differential diagnoses since pathologists may be called on to render a diagnosis on fine‐needle aspiration. Two cases of IFP are described with diagnostic features on imprint smears. Both were middle‐aged obese women with a history of prior intra‐abdominal surgical procedures who presented with signs of intestinal obstruction and were found to have a tumor causing intussuscption. At intraoperative consult, scrape cytology specimens showed cellular smears with a heterogeneous population of myofibroblasts, inflammatory cells and vessels. The features together with clinical history are sufficient to suggest the diagnosis. IFP is a lesion with a characteristic morphology. The differential diagnosis includes several other lesions, hence triage of cytological specimen for culture, electron microscopy, and immunohistochemistry is important in facilitating a correct diagnosis. Although a surgical procedure may still be necessary once a diagnosis of IFP is made, treatment may be tailored for a less aggressive process. Diagn. Cytopathol. 2003;28:217–221. © 2003 Wiley‐Liss, Inc.