Premium
Reliability of fine‐needle aspiration biopsy in the initial diagnosis of soft‐tissue lesions
Author(s) -
Nagira Keiko,
Yamamoto Tetsuji,
Akisue Toshihiro,
Marui Takashi,
Hitora Toshiaki,
Nakatani Tetsuya,
Kurosaka Masahiro,
Ohbayashi Chiho
Publication year - 2002
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.10200
Subject(s) - medicine , soft tissue , malignancy , fine needle aspiration , biopsy , medical diagnosis , radiology , cytopathology , lesion , cytology , trunk , pathology , ecology , biology
Abstract We retrospectively reviewed fine‐needle aspiration biopsy (FNAB) specimens of 301 soft tissue lesions of the extremities and trunk. Final diagnoses were 137 benign and 86 malignant neoplasms and 78 nonneoplastic lesions. Of the 301 FNAB samples, 279 (93%) were adequate for cytologic diagnosis. The adequate FNAB specimens were initially grouped into three broad categories: benign (197 cases), malignant (57 cases), and suspicious for malignancy (25 cases). Sensitivity and specificity for diagnosis of a malignant lesion were 92% and 97%, respectively. The specimens were cytomorphologically classified into nine categories: small round (14 cases), spindle cell (77 cases), epithelioid/polygonal (16 cases), pleomorphic (29 cases), myxoid (19 cases), lipomatous (37 cases), epithelial (23 cases), inflammatory lesions (28 cases), and others (36 cases). Specific FNAB diagnoses were correct in 151 of 279 cases (54%) in combination with clinical and radiologic findings. FNAB is a valuable technique for the primary diagnosis of soft‐tissue lesions. Diagn. Cytopathol. 2002;27:354–361. © 2002 Wiley‐Liss, Inc.