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Well‐differentiated villoglandular adenocarcinoma of the uterine cervix: Cytomorphologic observation of five cases
Author(s) -
Khunamornpong Surapan,
Siriaunkgul Sumalee,
Suprasert Prapaporn
Publication year - 2002
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.10028
Subject(s) - video graphics array , medicine , uterine cervix , pathology , nucleolus , cytology , adenocarcinoma , anatomy , cervix , nucleus , carcinoma , chip , cancer , psychiatry , electrical engineering , engineering
We retrospectively examined the cytologic findings of well‐differentiated villoglandular adenocarcinoma (VGA) treated in our hospital. Cervical smears of four cases and a touch preparation of another case of VGA formed the materials for the study. The cytologic features were correlated with the histomorphology of VGA. Architecturally, long slender papillae and cohesive branching epithelial sheets with smooth borders and a lack of feathery edge were observed. Crowding and overlapping of nuclei were noted. The nuclei were uniform, small, and round to oval‐shaped, with evenly distributed granular chromatin. Nucleoli were absent or inconspicuous. Mitoses were occasionally seen in all but one case. As the features of VGA are distinctive, the diagnosis could be possible on cytological grounds. Examination of cervical smears would be helpful for an early diagnosis of VGA or to suggest the coexistence of other neoplastic components. Diagn. Cytopathol. 2002;26:10–14. © 2002 Wiley‐Liss, Inc.