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THE IMPACT OF DISSOCIATION ON PTSD TREATMENT WITH COGNITIVE PROCESSING THERAPY
Author(s) -
Resick Patricia A.,
Suvak Michael K.,
Johnides Benjamin D.,
Mitchell Karen S.,
Iverson Katherine M.
Publication year - 2012
Publication title -
depression and anxiety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.634
H-Index - 129
eISSN - 1520-6394
pISSN - 1091-4269
DOI - 10.1002/da.21938
Subject(s) - dissociation (chemistry) , depersonalization , psychology , cognition , randomized controlled trial , clinical psychology , dissociative , multilevel model , psychiatry , medicine , chemistry , emotional exhaustion , burnout , machine learning , computer science
Background This secondary analysis of data from a randomized controlled trial of cognitive processing therapy ( CPT ) and its constituent components investigated whether dissociation decreased over the course of treatment primarily targeting symptoms of posttraumatic stress disorder ( PTSD ) and explored whether levels of dissociation predicted treatment outcome differentially by treatment condition . Methods An intention to treat sample of 150 women were randomized to CPT , cognitive therapy only ( CPT ‐ C ) or written trauma accounts only ( WA ). Dissociation was measured by the dissociation subscale of the T raumatic S tress I nventory and the M ultiscale D issociation I nventory . Results Multilevel regression analyses revealed significant decreases in dissociation that did not vary as a function of treatment condition. Growth curve modeling revealed significant treatment condition by dissociation interactions such that the impact of pretreatment levels of dissociation impacted the treatment conditions differently . Conclusions Women who endorsed low pretreatment levels of dissociation responded most efficiently to CPT ‐ C , whereas women with the highest levels of dissociation, in particular high levels of depersonalization, responded better to CPT .