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Parental predictors of pediatric panic disorder/agoraphobia: a controlled study in high‐risk offspring
Author(s) -
Biederman Joseph,
Petty Carter,
Faraone Stephen V.,
HirshfeldBecker Dina R.,
Henin Aude,
Dougherty Meghan,
LeBel Teresa J.,
Pollack Mark,
Rosenbaum Jerrold F.
Publication year - 2005
Publication title -
depression and anxiety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.634
H-Index - 129
eISSN - 1520-6394
pISSN - 1091-4269
DOI - 10.1002/da.20122
Subject(s) - agoraphobia , panic disorder , offspring , psychology , clinical psychology , psychiatry , medicine , anxiety , pregnancy , biology , genetics
Our objective was to evaluate parental risk factors for pediatric‐onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG ( N = 27) and parents with PD without children with PD or AG ( N = 79). Comparisons were also made between the spouses of these parents with PD. Separation anxiety disorder, social phobia, obsessive–compulsive disorder, and bipolar disorder in the parents with PD and their spouses accounted for the risk for childhood onset PD/AG in the offspring. This risk was particularly high if both parents were affected with social phobia. These findings suggest that psychiatric comorbidity with other anxiety disorders and with bipolar disorder in parents with PD and their spouses confer a particularly high risk in their offspring to develop PD/AG in childhood. Depression and Anxiety 22:114–120, 2005. © 2005 Wiley‐Liss, Inc.