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Personality disorder comorbidity in panic disorder patients with or without current major depression
Author(s) -
Iketani Toshiya,
Kiriike Nobuo,
Stein Murray B.,
Nagao Kouji,
Nagata Toshihiko,
Minamikawa Naomitsu,
Shidao Atsushi,
Fukuhara Hidehiro
Publication year - 2002
Publication title -
depression and anxiety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.634
H-Index - 129
eISSN - 1520-6394
pISSN - 1091-4269
DOI - 10.1002/da.10050
Subject(s) - comorbidity , panic disorder , personality disorders , psychology , major depressive disorder , clinical psychology , psychiatry , personality , borderline personality disorder , panic , depression (economics) , avoidant personality disorder , personality pathology , anxiety , mood , social psychology , economics , macroeconomics
To investigate the relationship between current or past major depressive disorder (MDD) on comorbid personality disorders in patients with panic disorder, we compared the comorbidity of personality disorders using the Structured Clinical Interview for DSM‐III‐R personality disorders (SCID‐II) in 34 panic disorder patients with current MDD (current‐MD group), 21 with a history of MDD but not current MDD (past‐MD group), and 32 without lifetime MDD comorbidity (non‐MD group). With regard to personality disorders, patients in the current‐MD group met criteria for at least one personality disorder significantly more often than patients in the past‐MD group or the non‐MD group (82.4% vs. 52.4% and 56.3%, respectively). The current‐MD group showed statistically significantly more borderline, dependent, and obsessive‐compulsive personality disorders than the past‐MD group or non‐MD group. With stepwise regression analyses, number of MDD episodes emerged as an indicator of the comorbidity of cluster C personality disorder and any personality disorders. Future studies should determine whether aggressive treatment of comorbid personality disorders improves the outcome (e.g., lowers the likelihood of comorbid MDD) of patients with panic disorder. © 2002 Wiley‐Liss, Inc.