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Hepatosplenic T‐Cell Lymphoma in an Immunocompetent Male with Central Nervous System Invasion: A Rare Clinical Entity
Author(s) -
Wu Fan,
Pan Ying,
Wang Huiping,
Tao Qianshan,
An Furun,
Zhang Jiakui,
Zhai Zhimin
Publication year - 2019
Publication title -
cytometry part b: clinical cytometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 61
eISSN - 1552-4957
pISSN - 1552-4949
DOI - 10.1002/cyto.b.21736
Subject(s) - hepatosplenomegaly , immunophenotyping , lymphoma , bone marrow , pathology , medicine , central nervous system , rare disease , disease , flow cytometry , immunology
Hepatosplenic T‐cell lymphoma (HSTCL) is a very rare non‐Hodgkin lymphoma with an aggressive clinical course and poor prognosis. Patients of this disease usually presented with hepatosplenomegaly, which can be misdiagnosed or delayed. Bone marrow (BM) and peripheral blood (PB) are frequently involved, however, central nervous system (CNS) involvement is less common. Here, we are reporting an unusual case of hepatosplenic γδ T‐cell lymphoma in a 64‐year‐old man with CNS involvement. Flow cytometry immunophenotyping was proved of great diagnostic contribution. © 2018 International Clinical Cytometry Society