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Flow cytometric detection of degranulated basophils in chronic myeloid leukemia in accelerated phase
Author(s) -
Stacchini Alessandra,
Demurtas Anna,
Godio Laura
Publication year - 2011
Publication title -
cytometry part b: clinical cytometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 61
eISSN - 1552-4957
pISSN - 1552-4949
DOI - 10.1002/cyto.b.20566
Subject(s) - degranulation , myeloid leukemia , flow cytometry , pathology , myeloid , medicine , immunology , biology , receptor
Abstract We report a rare case of chronic myeloid leukemia in accelerated phase with basophilic transformation, in which basophils exceeding 70%, were detectable only by flow cytometry because of their morphologic atypicality and degranulation. © 2010 Clinical Cytometry Society.