The central nervous system as target for antihypertensive actions of a proline‐rich peptide from  Bothrops jararaca  venom | Zendy

Lameu Claudiana | Zendy; Hayashi Mirian A. F. | Zendy; Guerreiro Juliano R. | Zendy; Oliveira Eduardo F. | Zendy; Lebrun Ivo | Zendy; Pontieri Vera | Zendy; Morais Kátia L. P. | Zendy; Camargo Antonio C. M. | Zendy; Ulrich Henning | Zendy

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The central nervous system as target for antihypertensive actions of a proline‐rich peptide from Bothrops jararaca venom

Author(s) -

Lameu Claudiana,

Hayashi Mirian A. F.,

Guerreiro Juliano R.,

Oliveira Eduardo F.,

Lebrun Ivo,

Pontieri Vera,

Morais Kátia L. P.,

Camargo Antonio C. M.,

Ulrich Henning

Publication year - 2010

Publication title -

cytometry part a

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.316

H-Index - 90

eISSN - 1552-4930

pISSN - 1552-4922

DOI - 10.1002/cyto.a.20860

Subject(s) - bradykinin , venom , pertussis toxin , peptide , bothrops jararaca , chemistry , calcium , calcium in biology , pharmacology , receptor , biochemistry , medicine , biology , snake venom , g protein

Pyroglutamyl proline‐rich oligopeptides, present in the venom of the pit viper Bothrops jararaca ( Bj ‐PROs), are the first described naturally occurring inhibitors of the angiotensin I‐converting enzyme (ACE). The inhibition of ACE by the decapeptide Bj ‐PRO‐10c (

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