Open AccessA natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid‐β and tau pathology
Author(s) -
Jiang Xiaowen,
Lu Hongyuan,
Li Jingda,
Liu Wenwu,
Wu Qiong,
Xu Zihua,
Qiao Qinglong,
Zhang Haotian,
Gao Huiyuan,
Zhao Qingchun
Publication year - 2020
Publication title -
clinical and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2001-1326
DOI - 10.1002/ctm2.50
Subject(s) - fyn , scaffold protein , chemistry , phosphorylation , amyloid precursor protein , gsk 3 , tau protein , amyloid precursor protein secretase , drug discovery , biochemistry , pharmacology , alzheimer's disease , medicine , proto oncogene tyrosine protein kinase src , signal transduction , disease , pathology
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