Open AccessA natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid‐β and tau pathology
Author(s) -
Jiang Xiaowen,
Lu Hongyuan,
Li Jingda,
Liu Wenwu,
Wu Qiong,
Xu Zihua,
Qiao Qinglong,
Zhang Haotian,
Gao Huiyuan,
Zhao Qingchun
Publication year - 2020
Publication title -
clinical and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2001-1326
DOI - 10.1002/ctm2.50
Subject(s) - fyn , scaffold protein , chemistry , phosphorylation , gsk 3 , drug discovery , amyloid precursor protein secretase , virtual screening , tau protein , amyloid precursor protein , pharmacology , biochemistry , medicine , alzheimer's disease , proto oncogene tyrosine protein kinase src , signal transduction , disease , pathology