Premium
Infrared Irradiation‐Assisted Solvent‐Free Pd‐Catalyzed (Hetero)aryl‐aryl Coupling via C−H Bond Activation
Author(s) -
Albano Gianluigi,
Decandia Gianfranco,
Capozzi Maria Annunziata M.,
Zappimbulso Nicola,
Punzi Angela,
Farinola Gianluca M.
Publication year - 2021
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.202101070
Subject(s) - aryl , catalysis , chemistry , context (archaeology) , solvent , photochemistry , green chemistry , combinatorial chemistry , organic synthesis , infrared , irradiation , functional group , organic chemistry , reaction mechanism , alkyl , polymer , nuclear physics , optics , biology , paleontology , physics
The increasing attention towards environmentally friendly synthetic protocols has boosted studies directed to the development of green and sustainable methods for direct C−H bond arylation of (hetero)arenes. In this context, here the infrared (IR) irradiation‐assisted solvent‐free Pd‐catalyzed direct C−H bond arylation of (hetero)arenes was achieved. Several heteroaryl‐aryl coupling reactions were described, also involving heterocycles commonly used as building blocks for the synthesis of organic semiconductors. The reaction tolerated many functional groups on the aromatic nuclei. The IR‐irradiation as the energy source compared favorably with thermal heating and, in combination with solvent‐free conditions, provided an important contribution to the development of protocols fitting with the principles of green chemistry.