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1,4‐Dioxane‐Tuned Catalyst‐Free Methylation of Amines by CO 2 and NaBH 4
Author(s) -
Guo Zhiqiang,
Zhang Bo,
Wei Xuehong,
Xi Chanjuan
Publication year - 2018
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201801037
Subject(s) - amine gas treating , catalysis , chemistry , surface modification , solvent , methylation , medicinal chemistry , green chemistry , combinatorial chemistry , organic chemistry , inorganic chemistry , reaction mechanism , biochemistry , gene
A catalyst‐free reductive functionalization of CO 2 with amines and NaBH 4 was developed. The N ‐methylation of amines was carried out with CO 2 as a C 1 building block and 1,4‐dioxane as the solvent. Notably, the six‐electron reduction of CO 2 to form the methyl group occurred simultaneously with formation of the C−N bond to give the N‐methylated amine.