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Dual Rh−Ru Catalysts for Reductive Hydroformylation of Olefins to Alcohols
Author(s) -
Rodrigues Fábio M. S.,
Kucmierczyk Peter K.,
Pineiro Marta,
Jackstell Ralf,
Franke Robert,
Pereira Mariette M.,
Beller Matthias
Publication year - 2018
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201800488
Subject(s) - hydroformylation , chemoselectivity , chemistry , catalysis , yield (engineering) , rhodium , organic chemistry , alcohol , double bond , domino , alkene , combinatorial chemistry , cascade reaction , reductive elimination , materials science , metallurgy
Abstract An active and selective dual catalytic system to promote domino hydroformylation–reduction reactions is described. Apart from terminal, di‐ and trisubstituted olefins, for the first time the less active internal C−C double bond of tetrasubstituted alkenes can also be utilized. As an example, 2,3‐dimethylbut‐2‐ene is converted into the corresponding n ‐alcohol with high yield (90 %) as well as regio‐ and chemoselectivity (>97 %). Key for this development is the use of a combination of Rh complexes with bulky monophosphite ligands and the Ru‐based Shvo's complex. A variety of aromatic and aliphatic alkenes can be directly used to obtain mainly linear alcohols.