Premium
Methylation of Polyols with Trimethylphosphate in the Presence of a Lewis or Brønsted Acid Catalyst
Author(s) -
Duclos MarieChristine,
Herbinski Aurélien,
Mora AnneSophie,
Métay Estelle,
Lemaire Marc
Publication year - 2018
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201701841
Subject(s) - alkylation , catalysis , chemistry , lewis acids and bases , brønsted–lowry acid–base theory , trifluoromethanesulfonate , organic chemistry , alkyl , solvent , lewis acid catalysis , methylation , biochemistry , gene
The alkylation of alcohols and polyols has been investigated with alkylphosphates in the presence of a Lewis or Brønsted acid catalyst. The permethylation of polyols was developed under solvent‐free conditions at 100 °C with either iron triflate or Aquivion PW98, affording the isolated products in yields between 52 and 95 %. The methodology was also adjusted to carry out peralkylation with longer alkyl chains.