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Anionic Extraction for Efficient Recovery of Biobased 2,3‐Butanediol—A Platform for Bulk and Fine Chemicals
Author(s) -
Drabo Peter,
Tiso Till,
Heyman Benedikt,
Sarikaya Eda,
Gaspar Paula,
Förster Jochen,
Büchs Jochen,
Blank Lars Mathias,
Delidovich Irina
Publication year - 2017
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201700899
Subject(s) - extraction (chemistry) , 2,3 butanediol , fermentation , chemistry , solvent , sulfuric acid , aqueous solution , organic chemistry
2,3‐Butanediol (BDO) presents a promising platform molecule for the synthesis of basic and fine chemicals. Biotechnological production of BDO from renewable resources with living microbes enables high concentrations in the fermentation broth. The recovery of high‐boiling BDO from an aqueous fermentation broth presents a subsequent challenge. A method is proposed for BDO isolation based on reversible complexation with phenylboronate in an anionic complex. BDO can be recovered by back‐extraction into an acidic solution. The composition of the extracted species was determined by NMR spectroscopy, MS, and GC–MS methods. The conditions of extraction and back‐extraction were optimized by using commercial BDO and finally applied to different fermentation broths. Up to 72–93 % BDO can be extracted and up to 80–90 % can be back‐extracted under the optimized conditions. Purified bio‐BDO was used in the presence of sulfuric acid for the synthesis of methyl ethyl ketone, an established organic solvent and discussed tailor‐made biofuel.