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Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry
Author(s) -
Hessel Volker,
Kralisch Dana,
Kockmann Norbert,
Noël Timothy,
Wang Qi
Publication year - 2013
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201200766
Subject(s) - flow chemistry , process (computing) , process engineering , explosive material , process design , computer science , process integration , nanotechnology , chemical process , biochemical engineering , materials science , chemistry , engineering , continuous flow , organic chemistry , operating system
Novel Process Windows make use of process conditions that are far from conventional practices. This involves the use of high temperatures, high pressures, high concentrations (solvent‐free), new chemical transformations, explosive conditions, and process simplification and integration to boost synthetic chemistry on both the laboratory and production scale. Such harsh reaction conditions can be safely reached in microstructured reactors due to their excellent transport intensification properties. This Review discusses the different routes towards Novel Process Windows and provides several examples for each route grouped into different classes of chemical and process‐design intensification.