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Metal‐Free Aerobic Alcohol Oxidation: Intensification under Three‐Phase Flow Conditions
Author(s) -
Aellig Christof,
Scholz David,
Hermans Ive
Publication year - 2012
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201200438
Subject(s) - chemistry , alcohol oxidation , catalysis , selectivity , alcohol , continuous flow , metal , oxygen , flow chemistry , phase (matter) , inorganic chemistry , space velocity , chemical engineering , organic chemistry , physics , mechanics , engineering
The selective oxidation of alcohols is a pivotal transformation within industrial and synthetic chemistry. In this contribution we use O 2 as terminal oxidant and (H)NO x species as oxygen shuttle in order to mediate the oxidation of primary and secondary alcohols under the influence of a solid acid catalyst. Process optimization and intensification through the use of a continuous three‐phase flow reactor is demonstrated. Space–time yields were found to increase by two orders of magnitude with respect to batch experiments, along with additional gains in selectivity and a decrease of N 2 O formation.