Premium
A General and Efficient Heterogeneous Gold‐Catalyzed Hydration of Nitriles in Neat Water under Mild Atmospheric Conditions
Author(s) -
Liu YongMei,
He Lin,
Wang MiaoMiao,
Cao Yong,
He HeYong,
Fan KangNian
Publication year - 2012
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201200203
Subject(s) - catalysis , caprolactam , chemistry , heterogeneous catalysis , nanotechnology , combinatorial chemistry , organic chemistry , materials science
Mild, efficient and general: Titania decorated with nanometer‐sized gold particles acts as an efficient catalyst for the selective hydration of a wide range of chemically diverse nitriles into valuable amides in neutral water, under mild atmospheric conditions (see image). The process shows promise for a facile and direct one‐pot synthesis of ε ‐caprolactam, an industrially important molecule, starting from 6‐aminocapronitrile.