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Selective Oxidative Decarboxylation of Amino Acids to Produce Industrially Relevant Nitriles by Vanadium Chloroperoxidase
Author(s) -
But Andrada,
Le Nôtre Jérôme,
Scott Elinor L.,
Wever Ron,
Sanders Johan P. M.
Publication year - 2012
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201200098
Subject(s) - decarboxylation , chemistry , vanadium , nitrile , acrylonitrile , oxidative decarboxylation , succinonitrile , organic chemistry , catalysis , salt (chemistry) , amino acid , biochemistry , electrode , electrolyte , copolymer , polymer
Industrial nitriles from biomass : Vanadium‐chloroperoxidase is successfully used to transform selectively glutamic acid into 3‐cyanopropanoic acid, a key intermediate for the synthesis of bio‐succinonitrile and bio‐acrylonitrile, by using a catalytic amount of a halide salt. This clean oxidative decarboxylation can be applied to mixtures of amino acids obtained from plant waste streams, leading to easily separable nitriles.