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Development of New Hydrogenations of Imines and Benign Reductive Hydroaminations: Zinc Triflate as a Catalyst
Author(s) -
Werkmeister Svenja,
Fleischer Steffen,
Zhou Shaolin,
Junge Kathrin,
Beller Matthias
Publication year - 2012
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201100633
Subject(s) - trifluoromethanesulfonate , hydroamination , zinc , catalysis , chemistry , organic chemistry , combinatorial chemistry
The hydrogenation of imines to amines in the presence of catalytic amounts of zinc triflate has been demonstrated for the first time. In addition, an efficient procedure for the reductive hydroamination of alkynes to amines is presented using zinc triflate as a catalyst precursor. In both protocols a variety of different functional groups are tolerated, and the reactions proceed smoothly in high yields.