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Heterogeneous Catalytic Hydrogenation Reactions in Continuous‐Flow Reactors
Author(s) -
Irfan Muhammad,
Glasnov Toma N.,
Kappe C. Oliver
Publication year - 2011
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201000354
Subject(s) - microreactor , flow chemistry , catalysis , continuous flow , continuous reactor , environmentally friendly , chemistry , heterogeneous catalysis , batch reactor , flow (mathematics) , hydrogen , catalytic hydrogenation , process engineering , chemical engineering , materials science , nanotechnology , organic chemistry , biochemical engineering , physics , engineering , ecology , mechanics , biology
Microreactor technology and continuous flow processing in general are key features in making organic synthesis both more economical and environmentally friendly. Heterogeneous catalytic hydrogenation reactions under continuous flow conditions offer significant benefits compared to batch processes which are related to the unique gas‐liquid‐solid triphasic reaction conditions present in these transformations. In this review article recent developments in continuous flow heterogeneous catalytic hydrogenation reactions using molecular hydrogen are summarized. Available flow hydrogenation techniques, reactors, commonly used catalysts and examples of synthetic applications with an emphasis on laboratory‐scale flow hydrogenation reactions are presented.