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A Design‐of‐Experiments Approach for the Optimization and Understanding of the Cross‐Metathesis Reaction of Methyl Ricinoleate with Methyl Acrylate
Author(s) -
Ho Thao T. T.,
Jacobs Tina,
Meier Michael A. R.
Publication year - 2009
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.200900091
Subject(s) - methyl acrylate , metathesis , catalysis , salt metathesis reaction , chemistry , acrylate , reaction conditions , organic chemistry , combinatorial chemistry , biochemical engineering , polymerization , polymer , copolymer , engineering
A design‐of‐experiments approach for the investigation of the cross‐metathesis of methyl ricinoleate with methyl acrylate is described. Two second‐generation metathesis initiators were studied using different reaction conditions, revealing optimal reaction conditions for each catalyst. Interestingly, the two catalysts showed completely different temperature response profiles. As a result of these investigations, suitable reaction conditions for the sustainable production of two value‐added chemical intermediates were derived. Moreover, the design‐of‐experiments approach provided valuable information for a thorough understanding of catalytic reactions that would be more difficult to obtain by classic approaches.