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Copper‐Catalyzed Highly Efficient Aerobic Oxidation of Alcohols under Ambient Conditions
Author(s) -
Jiang Nan,
Ragauskas Arthur J.
Publication year - 2008
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.200800144
Subject(s) - catalysis , allylic rearrangement , copper , chemistry , alcohol oxidation , bromide , selectivity , ambient pressure , solvent , primary (astronomy) , alcohol , turnover number , organic chemistry , inorganic chemistry , photochemistry , physics , astronomy , thermodynamics
Up the TEMPO : A novel, three‐component catalyst system consisting of acetamido‐TEMPO, copper bromide, and 4‐pyrrolidinopyridine not only gives the highest reported turnover frequencies (up to 200 turnovers per hour) for solvent‐free aerobic oxidation of primary alcohols to aldehydes at ambient temperature and pressure, but also displays exceptionally high selectivity toward benzylic and allylic primary alcohols.