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2‐phenyl thiazolidine — its growth and characterisation
Author(s) -
Umarani R.,
Eswaramoorthy S.,
Raju K. S.
Publication year - 1990
Publication title -
crystal research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 64
eISSN - 1521-4079
pISSN - 0232-1300
DOI - 10.1002/crat.2170251009
Subject(s) - thiazolidine , orthorhombic crystal system , moiety , crystallography , methylene , chemistry , ring (chemistry) , crystal structure , absorption spectroscopy , absorption (acoustics) , infrared spectroscopy , group (periodic table) , proton magnetic resonance , diffraction , stereochemistry , materials science , nuclear magnetic resonance , organic chemistry , optics , physics , composite material
The importance of 2‐phenyl thiazolidine lies in its being a model for penicillin, as the five‐membered thiazolidine ring happens to be the moiety of penicillin. This material is synthesised and crystallised (Tsukerman). The crystals are white in colour, transparent, needle‐shaped and of dimensions (0.2 × 0.3 × 0.4 mm 3 ). Employing X‐ray diffraction studies, it is found that the crystal belongs to the orthorhombic system with the unit cell parameters a = 8.388(1), b = 18.114(2) and c = 5.625(1) Å. The space group is P 2 1 2 1 2 1 and Z = 4. The absorption peaks pertaining to NH, NCS, methylene CH 2 and aromatic C 6 H 4 have been identified from the infrared absorption spectrum of the sample. The Proton Magnetic Resonance (PMR) spectrum fully accounts for the hydrogens in the sample thereby unambigiously supporting the proposed structure.