Premium
Various Molecular Arrangements Leading to Different Desolvation Rates: Research on the Stability of 2,7‐Dibromo‐9H‐carbazole Solvates
Author(s) -
Guo Xuran,
Chen Wei,
Wei Rongli,
Sui Jingchen,
Huang Xin,
Wang Na,
Liu Songqiang,
Wang Ting,
Hao Hongxun
Publication year - 2021
Publication title -
crystal research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 64
eISSN - 1521-4079
pISSN - 0232-1300
DOI - 10.1002/crat.202100059
Subject(s) - chemistry , dimethylacetamide , intermolecular force , carbazole , molecule , crystallography , intramolecular force , dimethylformamide , stacking , crystal structure , infrared spectroscopy , acetonitrile , thermal stability , thermogravimetric analysis , crystal (programming language) , solvent , stereochemistry , organic chemistry , programming language , computer science
The stability of solvates is very important in the field of crystal engineering. Molecular interaction and packing mode are important factors affecting the stability of solvates. In this study, 2,7‐dibromo‐9H‐carbazole is selected as the model compound to investigate the influence of molecular stacking mode on the stability of solvates. An anhydrous form and five solvates of 2,7‐dibromo‐9H‐carbazole are obtained by recrystallization. The desolvation phenomena of the five solvates are studied by thermogravimetric analysis, hot stage microscope, and infrared spectroscopy and it is found that the stability of the solvates is N , N ‐dimethylacetamide solvate > dimethyl sulfoxide solvate > N , N ‐dimethylformamide solvate > dioxane solvate > acetonitrile solvate. Crystal structures are analyzed by single crystal X‐ray diffraction and Hirshfeld surface analysis is also applied to analyze the intermolecular interactions in the crystals. The results show that the stability of the five solvates is related to the packing modes of the molecules in the crystal. It is suggested that the solute molecules and solvent molecules in the unstable solvates are arranged in the interlayer mode, while they are arranged in a staggered mode in stable solvates.