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Solubility and metastable zone width of DL‐tartaric acid in aqueous solution
Author(s) -
Zhang XiangYang,
Wang Xiaofang,
Hao Lin,
Yang Xiaowu,
Dang Leping,
Wei Hongyuan
Publication year - 2012
Publication title -
crystal research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 64
eISSN - 1521-4079
pISSN - 0232-1300
DOI - 10.1002/crat.201200166
Subject(s) - solubility , metastability , tartaric acid , dissolution , gravimetric analysis , enthalpy , nucleation , aqueous solution , chemistry , thermodynamics , analytical chemistry (journal) , chromatography , organic chemistry , physics , citric acid
Solubility and metastable zone width (MSZW) of DL‐tartaric acid (DL‐TA) in aqueous solution have been determined. Solubility of DL‐TA was measured in the temperature range from 0 to 50 °C at atmospheric pressure by means of the conventional polythermal method using Turbidity Monitoring Technique, which was verified by a gravimetric method. The dissolution enthalpy and entropy of DL‐TA were then calculated from the solubility data using van't Hoff equation. Two approaches was used to estimate the nucleation kinetics from the measured metastable zone width data, the self‐consistent approach and the approach based on 3D nucleation. In addition, the metastable zone width slightly decreases with increasing agitation rate and was independent of working volume.