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Ni 1‐ x Cr x alloy for self controlled magnetic hyperthermia
Author(s) -
Akin Y.,
Obaidat I. M.,
Issa B.,
Haik Y.
Publication year - 2009
Publication title -
crystal research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 64
eISSN - 1521-4079
pISSN - 0232-1300
DOI - 10.1002/crat.200800502
Subject(s) - curie temperature , materials science , chromium , alloy , magnetometer , analytical chemistry (journal) , squid , magnetic hyperthermia , curie , hyperthermia , nuclear magnetic resonance , magnetic semiconductor , magnetization , metallurgy , magnetic nanoparticles , condensed matter physics , doping , nanoparticle , chemistry , ferromagnetism , nanotechnology , magnetic field , optoelectronics , chromatography , ecology , biology , quantum mechanics , medicine , physics
It is known now that an increase in tumor temperature decreases the tumor resistance to chemo‐ and radiation therapies. Hyperthermia treatment of the tumor cells where damage to the healthy cells can be avoided is viable by using magnetic nanoparticles with controlled Curie temperatures. Nickel‐Chromium (Ni 1‐ x Cr x ) particles with varying compositions have been investigated as thermoseeds for use in localized self controlled hyperthermia treatment of cancer. A series of Ni 1‐ x Cr x alloys, have been prepared to find the specific composition which has Curie temperature around 316‐317 K. The samples were cast by arc melting technique, and were annealed at 850 o C for 5 hours in sealed quartz tubes. Magnetic properties of the samples were investigated, including Curie temperature, saturation magnetization and hysterisis using Superconducting Quantum Interference Device (SQUID) and Vibrating Sample Magnetometer (VSM). The Curie temperatures of the alloys were found to decrease almost linearly from 401 K to 289 K as the Cr concentration was increased from x = 4.54 wt% to x = 5.90 wt%. The results showed that Ni 1‐ x Cr x alloys might be good candidates for self regulating magnetic hyperthermia applications. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)