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Quetiapine‐ER vs. aripiprazole in psychosis in children and adolescents
Publication year - 2017
Publication title -
the brown university child and adolescent psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7567
pISSN - 1527-8395
DOI - 10.1002/cpu.30238
Subject(s) - quetiapine , aripiprazole , akathisia , psychiatry , psychosis , medicine , antipsychotic , psychology , schizophrenia (object oriented programming)
Adult studies do not necessarily help determine which antipsychotic medications work for children and adolescents, so research is needed to help guide clinicians treating young patients. In this head‐to‐head trial, they compared the efficacy and safety of quetiapine‐extended release (quetiapine‐ER) with aripiprazole. They found that there were no significant differences in psychopathology severity after 12 weeks of treatment. In terms of adverse events, there were more metabolic problems with quetiapine‐ER and more initial akathisia and sedation with aripiprazole.