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Nonpublication of pediatric RCTs twice as high for industry as academic‐sponsored trials
Publication year - 2016
Publication title -
the brown university child and adolescent psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7567
pISSN - 1527-8395
DOI - 10.1002/cpu.30154
Subject(s) - discontinuation , clinical trial , randomized controlled trial , medicine , family medicine , alternative medicine , pathology
Pediatric randomized clinical trials (RCTs) have specific challenges that can lead to discontinuation and nonpublication. Researchers looked at the prevalence of these and found that industry‐sponsored trials are less likely to be discontinued, probably due to the greater access to financial resources compared to academic trials. They also found that industry‐sponsored trials are more than twice as likely to go unpublished compared to academic trials, contributing to publication bias.